BDBM127928 US8796304, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-ethyl]-8-fluoro-5H-imidazo[2,1-a]isoindole

SMILES Cc1cnc(C)c2nc(CCc3cn4Cc5ccc(F)cc5-c4n3)nn12

InChI Key InChIKey=MGGLAMAUWUWJON-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 127928   

LigandPNGBDBM127928(US8796304, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 3.10nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent