BDBM12811 2,2,2-trifluoroacetic acid; N-(1,3-benzothiazol-6-yl)-2-(5-carbamimidoyl-1-benzothiophen-3-yl)-3-phenylpropanamide::5-Amidinobenzo[b]thiophene 29

SMILES NC(=N)c1ccc2scc(C(Cc3ccccc3)C(=O)Nc3ccc4ncsc4c3)c2c1

InChI Key InChIKey=WMOHPRLZMWOJBM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 12811   

TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM12811(2,2,2-trifluoroacetic acid; N-(1,3-benzothiazol-6-...)
Affinity DataKi:  780nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM12811(2,2,2-trifluoroacetic acid; N-(1,3-benzothiazol-6-...)
Affinity DataKi:  780nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM12811(2,2,2-trifluoroacetic acid; N-(1,3-benzothiazol-6-...)
Affinity DataKi: >8.00E+3nM ΔG°: >-6.88kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM12811(2,2,2-trifluoroacetic acid; N-(1,3-benzothiazol-6-...)
Affinity DataKi: >8.00E+3nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed