BDBM128219 (*R)-4-(((6-ethyl-4-oxochroman-7-yl)oxy)(pyridin-4-yl)methyl)benzamide::US12516038, Example 74a

SMILES CCc1cc2c(cc1O[C@@H](c1ccncc1)c1ccc(C(N)=O)cc1)OCCC2=O

InChI Key InChIKey=KTLQZJCDFXKFGW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 128219   

TargetHLA-DR4 protein(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 128219BDBM128219((*R)-4-(((6-ethyl-4-oxochroman-7-yl)oxy)(pyridin-4...)
Affinity DataIC50: 550nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2026
Entry Details
US Patent