BDBM12841 1-(3-amino-1,2-benzoxazol-5-yl)-N-[2-fluoro-4-(2-{[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]methyl}phenyl)phenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide::Aminobenzisoxazole 2j

SMILES Nc1noc2ccc(cc12)-n1nc(cc1C(=O)Nc1ccc(cc1F)-c1ccccc1CN1CCC[C@H]1CO)C(F)(F)F

InChI Key InChIKey=HRFLXDHXKFKMKT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12841   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM12841(1-(3-amino-1,2-benzoxazol-5-yl)-N-[2-fluoro-4-(2-{...)
Affinity DataKi:  0.200nM ΔG°:  -13.1kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2007
Entry Details Article
PubMed