BDBM128659 US8796244, 250
SMILES FC(F)(F)CNC(=O)Nc1cccc(c1)-c1cnc2cc(ccn12)-c1nnc(NC2CC2)s1
InChI Key InChIKey=IBSMXTBTUWUZJT-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 128659
Affinity DataIC50: 4.60nMpH: 8.0 T: 25°CAssay Description:Enzymes (from Upstate) were prepared at 2× final concentration in 1× kinase assay buffer (Table 1). Enzymes were then incubated with test compounds, ...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMpH: 8.0 T: 25°CAssay Description:VEGFR2 (from Upstate), prepared at 2x final concentration, was incubated with test compounds, biotinylated Flt3 substrate (biotin-VASSDNEYFYVDF) (Cel...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMpH: 8.0 T: 25°CAssay Description:Enzymes (from Upstate) were prepared at 2× final concentration in 1× kinase assay buffer (Table 1). Enzymes were then incubated with test compounds, ...More data for this Ligand-Target Pair