BDBM130305 US8815840, 319

SMILES CN1CCC(Nc2ccc3c(c2)[nH]c2c(C(N)=O)cc(-c4cccc(C(F)(F)F)c4)nc23)CC1

InChI Key InChIKey=PXRSXCPWLLZPKA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130305   

TargetTyrosine-protein kinase JAK2(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 130305BDBM130305(US8815840, 319)
Affinity DataIC50: 1nMpH: 7.4Assay Description:The assays were performed in V-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme and substrates (fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2015
Entry Details
US Patent