BDBM130316 US8815840, 374

SMILES NC(=O)c1cc(-c2cc(CN3CCOCC3)co2)nc2c1[nH]c1cc(N3CCOCC3)ccc12

InChI Key InChIKey=VOCBAFITFFMQAB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130316   

TargetTyrosine-protein kinase JAK2(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 130316BDBM130316(US8815840, 374)
Affinity DataIC50: 6nMpH: 7.4Assay Description:The assays were performed in V-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme and substrates (fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2015
Entry Details
US Patent