BDBM130384 6({[(2R,4S)4{[(6amino4methylpyridin2 yl)oxy]methyl}pyrrolidin2yl]methoxy}methyl)4 methylpyridin2amine ((2R,4S)-6)
SMILES Cc1cc(N)nc(COC[C@H]2C[C@H](COc3cc(C)cc(N)n3)CN2)c1
InChI Key InChIKey=YFPMURIHASNWOW-LSDHHAIUSA-N
Data 6 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 130384
Affinity DataKd: 50nMpH: 7.5 T: 25°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
TargetIsoform PNNOS of Nitric oxide synthase, brain (PNNOS) -973,I269V,M336V,D597N](Rat)
University of California Irvine
University of California Irvine
Affinity DataKd: 153nMpH: 7.5 T: 25°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
Affinity DataKd: 1.18E+3nMpH: 7.5 T: 25°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
Affinity DataKd: 1.60E+3nMpH: 7.5 T: 25°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
Affinity DataKd: 3.49E+3nMpH: 7.5 T: 25°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair
TargetIsoform PNNOS of Nitric oxide synthase, brain (PNNOS) -973,I269V,H341L](Rat)
University of California Irvine
University of California Irvine
Affinity DataKd: 352nMpH: 7.5 T: 25°CAssay Description:The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...More data for this Ligand-Target Pair