BDBM131844 US8835445, 20

SMILES COc1ccc2nc(SCCC(C)(F)F)n(-c3ccc4c(N)nc(N)nc4c3)c2c1

InChI Key InChIKey=IYGGBRFBQQVMSV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 131844   

TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131844(US8835445, 20)
Affinity DataKi:  0.120nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetDihydrofolate reductase(Human)
Trius Therapeutics

US Patent
LigandPNGBDBM131844(US8835445, 20)
Affinity DataKi:  586nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent