BDBM131886 US8835436, Example 4

SMILES CCCc1nc(cn1-c1ccc(Cl)cc1)C(=O)NCCN1CCN(CC1)c1cccc(Cl)c1Cl

InChI Key InChIKey=XEOCHFFUOJNUJC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 131886   

Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

US Patent
LigandChemical structure of BindingDB Monomer ID 131886BDBM131886(US8835436, Example 4)
Affinity DataIC50: 69nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

US Patent
LigandChemical structure of BindingDB Monomer ID 131886BDBM131886(US8835436, Example 4)
Affinity DataIC50: 136nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Green Cross

US Patent
LigandChemical structure of BindingDB Monomer ID 131886BDBM131886(US8835436, Example 4)
Affinity DataIC50: 1.09E+3nMpH: 7.4Assay Description:For serotonin transporter binding assays, a reaction mixture with a final volume of 0.25 ml was prepared by mixing a test compound, human serotonin t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent