BDBM131889 US8835436, Example 90

SMILES CCc1c(nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Br)cc1)C(=O)NCCCN1CCN(CC1)c1cccc(C)c1C

InChI Key InChIKey=PXWTVOJRXKUHBC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 131889   

Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

US Patent
LigandChemical structure of BindingDB Monomer ID 131889BDBM131889(US8835436, Example 90)
Affinity DataIC50: 127nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

US Patent
LigandChemical structure of BindingDB Monomer ID 131889BDBM131889(US8835436, Example 90)
Affinity DataIC50: 146nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Green Cross

US Patent
LigandChemical structure of BindingDB Monomer ID 131889BDBM131889(US8835436, Example 90)
Affinity DataIC50: 298nMpH: 7.4Assay Description:For serotonin transporter binding assays, a reaction mixture with a final volume of 0.25 ml was prepared by mixing a test compound, human serotonin t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent