BDBM131901 US8835436, Example 132

SMILES Cc1nc(C(=O)NCCCN2CCN(CC2)c2cccc(C)c2C)c(C)n1-c1ccccn1

InChI Key InChIKey=MKONVJWMCLCPCH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 131901   

TargetSodium-dependent serotonin transporter(Human)
Green Cross

US Patent
LigandPNGBDBM131901(US8835436, Example 132)
Affinity DataIC50: 12nMpH: 7.4Assay Description:For serotonin transporter binding assays, a reaction mixture with a final volume of 0.25 ml was prepared by mixing a test compound, human serotonin t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

US Patent
LigandPNGBDBM131901(US8835436, Example 132)
Affinity DataIC50: 297nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

US Patent
LigandPNGBDBM131901(US8835436, Example 132)
Affinity DataIC50: 388nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent