BDBM13241 4-methyl-2-[(phenylcarbamoyl)amino]-N-(2,4,6-trimethylphenyl)-1,3-thiazole-5-carboxamide::BMS-354825 2-Amino-4-methyl-thiazole Analog 8b

SMILES Cc1nc(NC(=O)Nc2ccccc2)sc1C(=O)Nc1c(C)cc(C)cc1C

InChI Key InChIKey=ZRHPGLYANANTSD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13241   

TargetProto-oncogene tyrosine-protein kinase LCK(Mus musculus)
Bristol-Myers Squibb

LigandPNGBDBM13241(4-methyl-2-[(phenylcarbamoyl)amino]-N-(2,4,6-trime...)
Affinity DataIC50:  90nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM13241(4-methyl-2-[(phenylcarbamoyl)amino]-N-(2,4,6-trime...)
Affinity DataIC50:  160nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed