BDBM13246 5-N-(2-chloro-6-methylphenyl)-2-N-cyclopropane-1,3-thiazole-2,5-diamido::BMS-354825 2-Carboxamido-4-hydrido-thiazole Analog 7n::CHEMBL131577::N-(2-chloro-6-methylphenyl)-2-[(cyclopropylcarbonyl)amino]-1,3-thiazole-5-carboxamide
SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(NC(=O)C2CC2)s1
InChI Key InChIKey=CQZZCFVTEOJWAW-UHFFFAOYSA-N
Data 16 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 13246
Affinity DataIC50: 35nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human LckMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of Fyn kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase HCK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of Hck kinaseMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of KDR kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of Jak3 kinaseMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of FAK kinaseMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CDK2 kinaseMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of HER2 kinaseMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of Src kinaseMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity of the compound against HER1 kinaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity of the compound human Lck(hLck) kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of Lck kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibitory activity human Lck(hLck) kinaseMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of FGF receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 880nMAssay Description:Inhibition of CD3/CD28 T-cell proliferation assay in PBL (peripheral blood lymphocytes)More data for this Ligand-Target Pair