BDBM133534 US8846719, 226::US8846719, 230

SMILES Cc1onc(c1COc1ccc(cn1)C(=O)NC1CC(C1)OCc1ccccc1)-c1ccccc1

InChI Key InChIKey=WOXGCAVUJHNRNQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 133534   

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandPNGBDBM133534(US8846719, 230 | US8846719, 226)
Affinity DataKi:  1.20nM ΔG°:  -11.3kcal/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandPNGBDBM133534(US8846719, 230 | US8846719, 226)
Affinity DataKi:  2.60nM ΔG°:  -10.9kcal/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent