BDBM13356 CHEMBL84624::N-(2-chloro-6-methylphenyl)-2-[(2,6-dimethylpyrimidin-4-yl)amino]-1,3-benzothiazole-6-carboxamide::benzothiazole analog 13

SMILES Cc1cc(Nc2nc3ccc(cc3s2)C(=O)Nc2c(C)cccc2Cl)nc(C)n1

InChI Key InChIKey=MPSLLCQEAHPHNF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13356   

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM13356(CHEMBL84624 | N-(2-chloro-6-methylphenyl)-2-[(2,6-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM13356(CHEMBL84624 | N-(2-chloro-6-methylphenyl)-2-[(2,6-...)
Affinity DataIC50:  20nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed