BDBM134019 US8846689, 21
SMILES COc1cc(ccc1Nc1ncc(c(Oc2cccc3CCC(=O)c23)n1)C(F)(F)F)C(=O)NC1CCN(C)CC1
InChI Key InChIKey=QUSSZSMDFABHLI-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 134019
Affinity DataIC50: 2nMpH: 7.5Assay Description:This test uses active PTK2 enzyme (Invitrogen Code PV3832) and poly-Glu-Tyr (4:1, Sigma P-0275) as the kinase substrate. The kinase activity is detec...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of human PTK2 (411-689 residues) expressed in Hi-5 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human PTK2 (411-689 residues) expressed in Hi-5 cellsMore data for this Ligand-Target Pair