BDBM134019 US8846689, 21

SMILES COc1cc(ccc1Nc1ncc(c(Oc2cccc3CCC(=O)c23)n1)C(F)(F)F)C(=O)NC1CCN(C)CC1

InChI Key InChIKey=QUSSZSMDFABHLI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 134019   

TargetFocal adhesion kinase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM134019(US8846689, 21)
Affinity DataIC50:  2nMpH: 7.5Assay Description:This test uses active PTK2 enzyme (Invitrogen Code PV3832) and poly-Glu-Tyr (4:1, Sigma P-0275) as the kinase substrate. The kinase activity is detec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM134019(US8846689, 21)
Affinity DataIC50:  17nMAssay Description:Inhibition of human PTK2 (411-689 residues) expressed in Hi-5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM134019(US8846689, 21)
Affinity DataIC50:  16nMAssay Description:Inhibition of human PTK2 (411-689 residues) expressed in Hi-5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed