BDBM13429 (2R,5S,15S)-2,15-dimethyl-14-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-yl sulfamate::dehydroepiandrosterone (DHEA) sulphamate 14

SMILES C[C@]12CCC3C(CC=C4C[C@H](CC[C@]34C)OS(N)(=O)=O)C1CCC2=O

InChI Key InChIKey=PGZGPYMGHNIKHG-INNQQZFDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13429   

TargetSteryl-sulfatase(Homo sapiens (Human))
St. Mary'S Hospital

LigandPNGBDBM13429((2R,5S,15S)-2,15-dimethyl-14-oxotetracyclo[8.7.0.0...)
Affinity DataIC50: >1.00E+4nMAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
St. Mary'S Hospital

LigandPNGBDBM13429((2R,5S,15S)-2,15-dimethyl-14-oxotetracyclo[8.7.0.0...)
Affinity DataIC50: >1.00E+4nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed