BDBM134400 US8846658, 117

SMILES NC1=N[C@@](c2cc(NC(=O)c3ncc(Br)cc3Cl)ccc2F)(C(F)F)COC1

InChI Key InChIKey=KLDFTGBUBUASGA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 134400   

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 134400BDBM134400(US8846658, 117)
Affinity DataIC50: 18nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent