BDBM135037 US8846698, 520

SMILES CC(C)(C)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(cc3)C#N)c2)c2cnc(N)nc12

InChI Key InChIKey=IMOYGBPQSLAZQR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 135037   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM135037(US8846698, 520)
Affinity DataIC50:  4.57nMAssay Description:Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so...More data for this Ligand-Target Pair
In DepthDetails US Patent