BDBM135053 US8846698, 538

SMILES COCC(C)(C)n1cc(C(=O)c2cncc(NC(=O)Cn3ccc(n3)C3CC3)c2)c2cncnc12

InChI Key InChIKey=RDPFLTKDDRWMSS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 135053   

TargetHigh affinity nerve growth factor receptor(Human)
Pfizer

US Patent
LigandPNGBDBM135053(US8846698, 538)
Affinity DataIC50:  1.51nMAssay Description:Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so...More data for this Ligand-Target Pair
In DepthDetails US Patent