BDBM135872 US8859596, 159

SMILES CCCCn1n(C)c(c\c1=N/C(=O)c1cc(ccc1ONC(C)C)C(F)(F)F)C(C)(C)C

InChI Key InChIKey=WRLBEGQDNOJOKV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 135872   

TargetCannabinoid receptor 2(Rat)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 135872BDBM135872(US8859596, 159)
Affinity DataKi:  5.20nMpH: 7.4Assay Description:HEK293 cells stably expressing rat CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogenized...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 135872BDBM135872(US8859596, 159)
Affinity DataKi:  16nM ΔG°:  -10.8kcal/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent