BDBM13615 3-Oxybenzamide 1::4-chloro-3-[2-(5-chloropyridin-2-yl)ethoxy]-N-{[1-(pyridin-4-yl)piperidin-4-yl]methyl}benzamide

SMILES Clc1ccc(CCOc2cc(ccc2Cl)C(=O)NCC2CCN(CC2)c2ccncc2)nc1

InChI Key InChIKey=AKPBXRZTJLYEEN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13615   

TargetCoagulation factor X(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universita£T

Curated by ChEMBL
LigandPNGBDBM13615(3-Oxybenzamide 1 | 4-chloro-3-[2-(5-chloropyridin-...)
Affinity DataKi:  19.9nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universita£T

Curated by ChEMBL
LigandPNGBDBM13615(3-Oxybenzamide 1 | 4-chloro-3-[2-(5-chloropyridin-...)
Affinity DataKi:  20nMAssay Description:Inhibitory activity against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universita£T

Curated by ChEMBL
LigandPNGBDBM13615(3-Oxybenzamide 1 | 4-chloro-3-[2-(5-chloropyridin-...)
Affinity DataKi:  20nM ΔG°:  -10.5kcal/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM13615(3-Oxybenzamide 1 | 4-chloro-3-[2-(5-chloropyridin-...)
Affinity DataKi:  5.40E+3nM ΔG°:  -7.18kcal/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed