BDBM13617 3-Oxybenzamide 3::3-[2-(4-chlorophenyl)ethoxy]-4-fluoro-N-{[1-(pyridin-4-yl)piperidin-4-yl]methyl}benzamide

SMILES Fc1ccc(cc1OCCc1ccc(Cl)cc1)C(=O)NCC1CCN(CC1)c1ccncc1

InChI Key InChIKey=SPSKAYMQPXKPMJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13617   

TargetCoagulation factor X(Human)
Rheinische Friedrich-Wilhelms-Universita£T

Curated by ChEMBL
LigandPNGBDBM13617(3-Oxybenzamide 3 | 3-[2-(4-chlorophenyl)ethoxy]-4-...)
Affinity DataKi:  39.8nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Rheinische Friedrich-Wilhelms-Universita£T

Curated by ChEMBL
LigandPNGBDBM13617(3-Oxybenzamide 3 | 3-[2-(4-chlorophenyl)ethoxy]-4-...)
Affinity DataKi:  40nMAssay Description:Inhibitory activity against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Rheinische Friedrich-Wilhelms-Universita£T

Curated by ChEMBL
LigandPNGBDBM13617(3-Oxybenzamide 3 | 3-[2-(4-chlorophenyl)ethoxy]-4-...)
Affinity DataKi:  40nM ΔG°:  -10.1kcal/molepH: 7.8 T: 25°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Aventis Pharma Deutschland

LigandPNGBDBM13617(3-Oxybenzamide 3 | 3-[2-(4-chlorophenyl)ethoxy]-4-...)
Affinity DataKi:  5.62E+3nM ΔG°:  -7.16kcal/molepH: 7.8 T: 25°CAssay Description:The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed