BDBM136184 US8853193, 21-2
SMILES CC(Oc1ncccc1Nc1ncnc2sc(C(O)=O)c(C)c12)C(F)(F)F
InChI Key InChIKey=MOIMTYHINWJRFX-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 136184
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 15nMpH: 7.4 T: 30°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair