BDBM136274 US8853193, 32-4

SMILES Cc1c(sc2ncnc(Nc3ccc(F)cc3OCC(F)F)c12)C(O)=O

InChI Key InChIKey=OKBFQQYIAVMKIC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136274   

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM136274(US8853193, 32-4)
Affinity DataIC50:  13nMpH: 7.4 T: 30°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In DepthDetails US Patent