BDBM136277 US8853193, 32.7
SMILES CC(CF)Oc1cc(F)ccc1Nc1ncnc2sc(C(O)=O)c(C)c12
InChI Key InChIKey=HBFUEXHRWJRBKF-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 136277
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 5nMpH: 7.4 T: 30°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair