BDBM13642 3-Oxybenzamide 28::3-[2-(2,4-dichlorophenyl)ethoxy]-4-methyl-N-{[1-(pyridin-4-yl)piperidin-4-yl]methyl}benzamide

SMILES Cc1ccc(cc1OCCc1ccc(Cl)cc1Cl)C(=O)NCC1CCN(CC1)c1ccncc1

InChI Key InChIKey=QPHKHBUNEICWPT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13642   

TargetCoagulation factor X(Human)
Aventis Pharma Deutschland

LigandPNGBDBM13642(3-Oxybenzamide 28 | 3-[2-(2,4-dichlorophenyl)ethox...)
Affinity DataKi:  37nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Aventis Pharma Deutschland

LigandPNGBDBM13642(3-Oxybenzamide 28 | 3-[2-(2,4-dichlorophenyl)ethox...)
Affinity DataKi:  37nMAssay Description:Inhibitory activity against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Aventis Pharma Deutschland

LigandPNGBDBM13642(3-Oxybenzamide 28 | 3-[2-(2,4-dichlorophenyl)ethox...)
Affinity DataKi:  55nMAssay Description:Binding affinity to human factor 10a using S-2765 as substrate preincubated for 15 mins followed by substrate addition measured between 1 and 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Aventis Pharma Deutschland

LigandPNGBDBM13642(3-Oxybenzamide 28 | 3-[2-(2,4-dichlorophenyl)ethox...)
Affinity DataKi:  4.87E+3nMAssay Description:The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed