BDBM136692 US8865686, Table 1, Compound 4

SMILES CN(C)C1C2CC3C(=C(O)C2(O)C(=O)C(C(=O)NCNc2cccc(C(O)=O)c2C(O)=O)=C1O)C(=O)c1c(O)cccc1C3(C)O

InChI Key InChIKey=GDFMZNWMFGDDBZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136692   

TargetTyrosyl-DNA phosphodiesterase 1(Human)
The United States of America, As Represented By The Secretary, Dept. of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 136692BDBM136692(US8865686, Table 1, Compound 4)
Affinity DataIC50: 4.90E+4nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent