BDBM136701 US8865662, 4

SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C(=O)N2CCOCC2)[C@@](C)(C[C@@H](C)C(=O)[C@H](C)C2N(CCCOc3cc(ccc3OC)C(=O)Nc3c(Cl)cncc3Cl)C(=O)O[C@]12C)OC

InChI Key InChIKey=ZVPLCPWZKIDEGY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136701   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Basilea Pharmaceutica

US Patent
LigandPNGBDBM136701(US8865662, 4)
Affinity DataIC50: 30nMpH: 7.2Assay Description:PDE4 specifically hydrolyzes cAMP and releases the product AMP. The potency of PDE inhibition by said agents is determined in an in vitro enzymatic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent