BDBM13749 (5S)-2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-methyl-5-(propan-2-yl)-4,5-dihydro-1,3-thiazol-4-one::(S)-2-((S)-1-(2-fluorophenyl)ethylamino)-5-isopropyl-5-methylthiazol-4(5H)-one::2-(S)-Phenethylamine analog 11

SMILES CC(C)[C@]1(C)SC(N[C@@H](C)c2ccccc2F)=NC1=O

InChI Key InChIKey=PKOUEAKRBUYDJE-BONVTDFDSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13749   

LigandPNGBDBM13749((5S)-2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-met...)
Affinity DataKi:  4nM ΔG°:  -11.3kcal/molepH: 7.2 T: 22°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed