BDBM13800 2-(3-aminopiperidin-1-yl)-1-{[2-(trifluoromethyl)phenyl]methyl}-1H,4H,9H-naphtho[2,3-d]imidazole-4,9-dione::Xanthine mimetic compound 15

SMILES NC1CCCN(C1)c1nc2c(C(=O)c3ccccc3C2=O)n1Cc1ccccc1C(F)(F)F

InChI Key InChIKey=RYSKFXDNLZWOKH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 13800   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13800(2-(3-aminopiperidin-1-yl)-1-{[2-(trifluoromethyl)p...)
Affinity DataKi:  25nM ΔG°:  -10.3kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13800(2-(3-aminopiperidin-1-yl)-1-{[2-(trifluoromethyl)p...)
Affinity DataKi: >3.00E+3nM ΔG°: >-7.45kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13800(2-(3-aminopiperidin-1-yl)-1-{[2-(trifluoromethyl)p...)
Affinity DataKi: >3.00E+4nM ΔG°: >-6.10kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed