BDBM138267 US8871738, 50

SMILES COc1cc(F)c(-c2ccc(C(=O)O)cc2C)cc1-c1ccc(C(F)(F)F)cc1[C@@H]1C=C[C@H]2[C@@H](c3cc(C(F)(F)F)cc(C(F)(F)F)c3)OC(=O)N12

InChI Key InChIKey=HCWQPSAVHRZKAV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 138267   

TargetCholesteryl ester transfer protein(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 138267BDBM138267(US8871738, 50)
Affinity DataIC50: 47.9nMpH: 7.4 T: 2°CAssay Description:First, low density lipoprotein (LDL) (Meridian) was biotinylated by incubating LDL with biotin for 1 hour on ice, after which it was dialyzed to remo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent