BDBM13945 APC-13140::[amino(2-{hydroxy[(3-phenoxyphenyl)methyl]carbamoyl}-1H-1,3-benzodiazol-5-yl)methylidene]azanium

SMILES NC(=[NH2+])c1ccc2nc(C(=O)N(O)Cc3cccc(Oc4ccccc4)c3)[nH]c2c1

InChI Key InChIKey=JEEKJSJMJKETGC-UHFFFAOYSA-O

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 13945   

TargetSerine protease 1(Bovine)
Axys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13945BDBM13945([amino(2-{hydroxy[(3-phenoxyphenyl)methyl]carbamoy...)
Affinity DataKi:  380nM ΔG°:  -8.66kcal/molepH: 7.7 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13945BDBM13945([amino(2-{hydroxy[(3-phenoxyphenyl)methyl]carbamoy...)
Affinity DataKi:  400nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2007
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Axys Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 13945BDBM13945([amino(2-{hydroxy[(3-phenoxyphenyl)methyl]carbamoy...)
Affinity DataKi:  3.80E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2007
Entry Details Article
PubMed