BDBM139675 US8894989, 57

SMILES CC(C)c1ccc(S(=O)(=O)N2CCN(CC3=Nc4cccc5c(=O)[nH]nc(c45)N3)CC2)cc1

InChI Key InChIKey=JTCBWEHMCWPRHW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139675   

TargetPoly [ADP-ribose] polymerase 1(Human)
Eisai

US Patent
LigandChemical structure of BindingDB Monomer ID 139675BDBM139675(US8894989, 57)
Affinity DataIC50: 17nMpH: 8.0Assay Description:A convenient method to determine IC50 of a PARP inhibitor compound is a PARP assay using purified recombinant human PARP from Trevigan (Gaithersburg,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2015
Entry Details
US Patent