BDBM139677 US8894989, 59::US8894989, 63

SMILES CC(C)c1ccc(S(=O)(=O)N2CCCN(CC3=Nc4cccc5c(=O)[nH]nc(c45)N3)CC2)cc1

InChI Key InChIKey=JJGMVDAGYLREBJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 139677   

TargetPoly [ADP-ribose] polymerase 1(Human)
Eisai

US Patent
LigandChemical structure of BindingDB Monomer ID 139677BDBM139677(US8894989, 63 | US8894989, 59)
Affinity DataIC50: 19nMpH: 8.0Assay Description:A convenient method to determine IC50 of a PARP inhibitor compound is a PARP assay using purified recombinant human PARP from Trevigan (Gaithersburg,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2015
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Eisai

US Patent
LigandChemical structure of BindingDB Monomer ID 139677BDBM139677(US8894989, 63 | US8894989, 59)
Affinity DataIC50: 23nMpH: 8.0Assay Description:A convenient method to determine IC50 of a PARP inhibitor compound is a PARP assay using purified recombinant human PARP from Trevigan (Gaithersburg,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2015
Entry Details
US Patent