BDBM139683 US8894989, 65

SMILES O=c1[nH]nc2c3c(cccc13)N=C(CN1CCCN(S(=O)(=O)c3ccc(-c4ccccc4)cc3)CC1)N2

InChI Key InChIKey=PLXLVZBDQOWZGB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139683   

TargetPoly [ADP-ribose] polymerase 1(Human)
Eisai

US Patent
LigandChemical structure of BindingDB Monomer ID 139683BDBM139683(US8894989, 65)
Affinity DataIC50: 22nMpH: 8.0Assay Description:A convenient method to determine IC50 of a PARP inhibitor compound is a PARP assay using purified recombinant human PARP from Trevigan (Gaithersburg,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2015
Entry Details
US Patent