BDBM139868 US8895581, V-9

SMILES CN(C)CCCc1nc2cnc3ccc(cc3c2n1C)C#CCNC(=O)c1cncn(Cc2ccc(F)c(F)c2)c1=O

InChI Key InChIKey=VFGIDIHUGCLMAY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139868   

Target3-phosphoinositide-dependent protein kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM139868(US8895581, V-9)
Affinity DataIC50: 6nMpH: 7.5Assay Description:Recombinant human PDK1 enzyme (aa 52-556) linked at its N-terminal end to His6 is isolated from baculovirus-infected insect cells. Purified enzyme ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent