BDBM142014 US8927539, 1

SMILES CC(=C)CC1(CCN(C(=O)O1)C(C)(C)C#Cc1ccc(F)cc1)c1ccccc1

InChI Key InChIKey=XPXQTBUMBSVDNW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142014   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM142014(US8927539, 1)
Affinity DataIC50: 3.70nMpH: 7.4Assay Description:The inhibition of a microsomal preparation of 11beta -HSD1 by compounds of the invention was measured essentially as previously described (K. Solly, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent