BDBM142620 US8933228, 11

SMILES CCn1c(=O)[nH]c2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)nn4-c4ccc(OC)cc4)c4ccccc34)c21

InChI Key InChIKey=HYEOMJSVLMONGY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 142620   

TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 142620BDBM142620(US8933228, 11)
Affinity DataIC50: 2nMAssay Description:The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
US Patent

TargetTyrosine-protein kinase HCK(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 142620BDBM142620(US8933228, 11)
Affinity DataIC50: 5nMAssay Description:The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 142620BDBM142620(US8933228, 11)
Affinity DataIC50: 9nMAssay Description:The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
US Patent

TargetMitogen-activated protein kinase 12(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 142620BDBM142620(US8933228, 11)
Affinity DataIC50: 348nMAssay Description:The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
US Patent