BDBM142704 US8937084, 6

SMILES Oc1ccc(CN2cc3[C@H]4Cc5ccc(O)cc5[C@@]3(CCN4CC3CC3)CC2=O)cc1

InChI Key InChIKey=IGZBIWQCMVZOKV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 142704   

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM142704(US8937084, 6)
Affinity DataKi:  1.27nM ΔG°:  -13.1kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for u-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM142704(US8937084, 6)
Affinity DataKi:  22.8nM ΔG°:  -11.3kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for u-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
US Patent