BDBM142705 US8937084, 7
SMILES Oc1ccc2C[C@@H]3[C@@H]4CNC(=O)C[C@]4(CCN3CC3CC3)c2c1
InChI Key InChIKey=XYEIPZFSMVUKKD-YQVWRLOYSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 142705
Affinity DataKi: 0.180nM ΔG°: -14.4kcal/molepH: 7.4 T: 50°CAssay Description:Radioligand dose-displacement binding assays for u-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane...More data for this Ligand-Target Pair
Affinity DataKi: 5.61nM ΔG°: -12.2kcal/molepH: 7.4 T: 50°CAssay Description:Radioligand dose-displacement binding assays for u-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane...More data for this Ligand-Target Pair
Affinity DataKi: 15.0nM ΔG°: -11.6kcal/molepH: 7.4 T: 50°CAssay Description:Radioligand dose-displacement binding assays for u-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane...More data for this Ligand-Target Pair