BDBM143688 US9572802, Compound I-7::US9682957, I-7

SMILES CN(CCCC(=O)Nc1cccc(CCNC[C@H](O)c2ccc(O)c3[nH]c(=O)ccc23)c1)C(=O)CCN1CCC(CC1)OC(=O)Nc1ccccc1-c1ccccc1

InChI Key

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 143688   

TargetMuscarinic acetylcholine receptor M3(Human)
Theravance Respiratory

US Patent
LigandPNGBDBM143688(US9572802, Compound I-7 | US9682957, I-7)
Affinity DataKi:  0.100nMAssay Description:Radioligand binding assays for cloned muscarinic receptors were performed in 96-well microtiter plates in a total assay volume of 100 μL. CHO ce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMuscarinic acetylcholine receptor M3(Human)
Theravance Respiratory

US Patent
LigandPNGBDBM143688(US9572802, Compound I-7 | US9682957, I-7)
Affinity DataKi:  0.100nMAssay Description:compounds were performed with [3H]NMS at 1 nM and eleven different test compound concentrations. The test compounds were initially dissolved to a con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetBeta-2 adrenergic receptor(Human)
Theravance Respiratory

US Patent
LigandPNGBDBM143688(US9572802, Compound I-7 | US9682957, I-7)
Affinity DataEC50:  1nMT: 25°CAssay Description:cAMP assays were performed in a radioimmunoassay format using the Flashplate Adenylyl Cyclase Activation Assay System with [125I]-cAMP (NEN SMP004, P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent