BDBM144215 US8969335, A40

SMILES N#Cc1cc(ccc1OC1CCOCC1)-c1ccnc(Nc2cnn(c2)C2CCNC2)n1

InChI Key InChIKey=CIBVSEISWWXHEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 144215   

LigandPNGBDBM144215(US8969335, A40)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:1 nM IKKe, 800 nM biotinylated IkBalpha(19-42) peptide (Biotin-C6-C6-GLKKERLLDDRHDSGLDSMKDEE) and 10 M ATP (spiked with 0.3 uCi of 33P-ATP/well) are ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase TBK1(Human)
Merck Patent

US Patent
LigandPNGBDBM144215(US8969335, A40)
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:The kinase assay is performed as 384-well flashplate assay (for example for Topcount measurement).0.6 nM TANK binding kinase (TBK1), 800 nM biotinyla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2015
Entry Details
US Patent