BDBM144421 US8969376, 1.187

SMILES CC(C)Cc1nc(-c2cc3nc(cc(NCC(C)(C)O)n3n2)N2CCCC2)c(C)nc1C

InChI Key InChIKey=SGRMTLFSTVHZBB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144421   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM144421(US8969376, 1.187)
Affinity DataIC50: 0.600nMpH: 8.0Assay Description:The PDE assay was performed according to a modified method referred to a report of Kotera et al. (Kotera et al., Biochem. Pharmacol., vol. 60, pp. 13...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent