BDBM144423 US8969376, 1.190

SMILES Cc1nc(C)c(nc1C1CC1)-c1cc2nc(cc(NC3CCOCC3)n2n1)N1CCCC1

InChI Key InChIKey=PDBSUFZTMYZVEX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144423   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM144423(US8969376, 1.190)
Affinity DataIC50: 0.690nMpH: 8.0Assay Description:The PDE assay was performed according to a modified method referred to a report of Kotera et al. (Kotera et al., Biochem. Pharmacol., vol. 60, pp. 13...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent