BDBM14475 (-)-1-(3-Bromo-7,8-dichloro-6,11-dihydro-5H-benzo-[5,6]cyclohepta[1,2-b]pyridin-11(S)-yl)-4-(4-pyridin-ylacetyl)-piperazine N4-Oxide::4-(2-{4-[(2S)-6-bromo-12,13-dichloro-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl]piperazin-1-yl}-2-oxoethyl)-1-oxidopyridin-1-ium::Trihalobenzocycloheptapyridine Tricyclic Compound 60

SMILES [O-][n+]1ccc(CC(=O)N2CCN(CC2)[C@H]2c3ccc(Cl)c(Cl)c3CCc3cc(Br)cnc23)cc1

InChI Key InChIKey=MKGYPBDRQKFJKZ-VWLOTQADSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14475   

LigandPNGBDBM14475((-)-1-(3-Bromo-7,8-dichloro-6,11-dihydro-5H-benzo-...)
Affinity DataIC50:  6nMpH: 7.5 T: 22°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed