BDBM14599 CHEMBL333980::N-[(4-carbamimidoylphenyl)methyl]-2-[2-methoxy-6-phenyl-3-(propan-2-ylamino)phenyl]acetamide::N-{4-[Amino(imino)methyl]benzyl}-2-[4-(isopropylamino)-3-methoxy-1,1-biphenyl-2-yl]acetamide::Substituted Benzene Analog 50e

SMILES COc1c(NC(C)C)ccc(-c2ccccc2)c1CC(=O)NCc1ccc(cc1)C(N)=N

InChI Key InChIKey=YVHLXJWWXOTYST-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 14599   

TargetCoagulation factor VII(Human)
Pharmacia

LigandPNGBDBM14599(N-[(4-carbamimidoylphenyl)methyl]-2-[2-methoxy-6-p...)
Affinity DataIC50: 1.47E+4nMpH: 8.0 T: 2°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

LigandPNGBDBM14599(N-[(4-carbamimidoylphenyl)methyl]-2-[2-methoxy-6-p...)
Affinity DataIC50: 7.90E+3nMpH: 8.0 T: 2°CAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

LigandPNGBDBM14599(N-[(4-carbamimidoylphenyl)methyl]-2-[2-methoxy-6-p...)
Affinity DataIC50: 3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human Factor Xa and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

LigandPNGBDBM14599(N-[(4-carbamimidoylphenyl)methyl]-2-[2-methoxy-6-p...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity against coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

LigandPNGBDBM14599(N-[(4-carbamimidoylphenyl)methyl]-2-[2-methoxy-6-p...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

LigandPNGBDBM14599(N-[(4-carbamimidoylphenyl)methyl]-2-[2-methoxy-6-p...)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibitory activity against tissue coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed