BDBM14602 Benzoquinone Analog 54::N-[(4-carbamimidoylphenyl)methyl]-2-[3,6-dioxo-2-phenyl-5-(propan-2-ylamino)cyclohexa-1,4-dien-1-yl]acetamide

SMILES [#6]\[#6](-[#6])=[#7]\c1cc(-[#8])c(-c2ccccc2)c(-[#6]-[#6](=O)-[#7]-[#6]-c2ccc(cc2)-[#6](-[#7])=[#7])c1-[#8]

InChI Key InChIKey=GYUSZJXULZQUJI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 14602   

TargetCoagulation factor VII(Human)
Pharmacia

LigandPNGBDBM14602(N-[(4-carbamimidoylphenyl)methyl]-2-[3,6-dioxo-2-p...)
Affinity DataIC50: 2.80E+3nMpH: 8.0 T: 2°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

LigandPNGBDBM14602(N-[(4-carbamimidoylphenyl)methyl]-2-[3,6-dioxo-2-p...)
Affinity DataIC50: 3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

LigandPNGBDBM14602(N-[(4-carbamimidoylphenyl)methyl]-2-[3,6-dioxo-2-p...)
Affinity DataIC50: 3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human Factor Xa and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed