BDBM149351 US8962859, 14

SMILES Cc1ccc(-c2cc(F)c3c(c2)[C@]2(N=C(N)n4ccnc42)c2cc(-c4cccnc4F)ccc2O3)cc1

InChI Key InChIKey=ZKCJVDNRTDFWSR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 149351   

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 149351BDBM149351(US8962859, 14)
Affinity DataIC50: 114nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
US Patent